Linda J. Popplewell : rechercher sur Z-Library

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1

β-catenin as a potential key target for tumor suppression

Yuejun Fu, Shuhua Zheng, Na An, Takis Athanasopoulos, Linda Popplewell, Aihua Liang, Ke Li, Changchen Hu, Yajing Zhu

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 327 KB

english, 2011

2

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

Linda J. Popplewell, Carl Adkin, Virginia Arechavala-Gomeza, Annemieke Aartsma-Rus, Christa L. de Winter, Steve D. Wilton, Jennifer E. Morgan, Francesco Muntoni, Ian R. Graham, George Dickson

Journal:

Neuromuscular Disorders

Année:

2010

Langue:

english

Fichier:

PDF, 655 KB

english, 2010

3

Gene Correction of a Duchenne Muscular Dystrophy Mutation by Meganuclease-Enhanced Exon Knock-In

Popplewell, Linda, Koo, Taeyoung, Leclerc, Xavier, Duclert, Aymeric, Mamchaoui, Kamel, Gouble, Agnés, Mouly, Vincent, Voit, Thomas, Pâques, Frédéric, Cédrone, Frédéric, Isman, Olga, Yáñez-Muñoz, Rafae

Journal:

Human Gene Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 629 KB

english, 2013

4

Triple Trans-Splicing Adeno-Associated Virus Vectors Capable of Transferring the Coding Sequence for Full-Length Dystrophin Protein into Dystrophic Mice

Koo, Taeyoung, Popplewell, Linda, Athanasopoulos, Takis, Dickson, George

Journal:

Human Gene Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2014

5

New developments in the use of gene therapy to treat Duchenne muscular dystrophy

Jarmin, Susan, Kymalainen, Hanna, Popplewell, Linda, Dickson, George

Journal:

Expert Opinion on Biological Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 820 KB

english, 2014

6

Antisense-induced Myostatin Exon Skipping Leads to Muscle Hypertrophy in Mice Following Octa guanidine Morpholino Oligomer Treatment

Kang, Jagjeet K, Malerba, Alberto, Popplewell, Linda, Foster, Keith, Dickson, George

Journal:

Molecular Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 242 KB

english, 2011

7

Gene therapy for muscular dystrophy: current progress and future prospects

Trollet, Capucine, Athanasopoulos, Takis, Popplewell, Linda, Malerba, Alberto, Dickson, George

Journal:

Expert Opinion on Biological Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2009

8

Delivery of AAV2/9-Microdystrophin Genes Incorporating Helix 1 of the Coiled-Coil Motif in the C-Terminal Domain of Dystrophin Improves Muscle Pathology and Restores the Level of α1-Syntrophin and α-Dystrobrevin in Skeletal Muscles of mdx Mice

Koo, Taeyoung, Malerba, Alberto, Athanasopoulos, Takis, Trollet, Capucine, Boldrin, Luisa, Ferry, Arnaud, Popplewell, Linda, Foster, Helen, Foster, Keith, Dickson, George

Journal:

Human Gene Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 854 KB

english, 2011

9

Genetic Therapeutic Approaches for Duchenne Muscular Dystrophy

Foster, Helen, Popplewell, Linda, Dickson, George

Journal:

Human Gene Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

10

Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy

Malerba, Alberto, Kang, Jagjeet K, McClorey, Graham, Saleh, Amer F, Popplewell, Linda, Gait, Michael J, Wood, Matthew JA, Dickson, George

Journal:

Molecular Therapy — Nucleic Acids

Année:

2012

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2012

11

Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice

Lu-Nguyen, Ngoc B, Jarmin, Susan A, Saleh, Amer F, Popplewell, Linda, Gait, Michael J, Dickson, George

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2015

12

Design of Phosphorodiamidate Morpholino Oligomers (PMOs) for the Induction of Exon Skipping of the Human DMD Gene

Popplewell, Linda J, Trollet, Capucine, Dickson, George, Graham, Ian R

Journal:

Molecular Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 884 KB

english, 2009

13

Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells

Massouridès, Emmanuelle, Polentes, Jérôme, Mangeot, Philippe-Emmanuel, Mournetas, Virginie, Nectoux, Juliette, Deburgrave, Nathalie, Nusbaum, Patrick, Leturcq, France, Popplewell, Linda, Dickson, Geor

Journal:

Skeletal Muscle

Année:

2015

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2015

14

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing

Klein, Pierre, Oloko, Martine, Roth, Fanny, Montel, Valérie, Malerba, Alberto, Jarmin, Susan, Gidaro, Teresa, Popplewell, Linda, Perie, Sophie, Lacau St Guily, Jean, de la Grange, Pierre, Antoniou, Mi

Journal:

Nucleic Acids Research

Année:

2016

Langue:

english

Fichier:

PDF, 6.74 MB

english, 2016

15

Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice

Lu-Nguyen, Ngoc, Malerba, Alberto, Popplewell, Linda, Schnell, Fred, Hanson, Gunnar, Dickson, George

Journal:

Molecular Therapy — Nucleic Acids

Année:

2017

Langue:

english

Fichier:

PDF, 5.28 MB

english, 2017

16

Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9

Koo, Taeyoung, Lu-Nguyen, Ngoc B., Malerba, Alberto, Kim, Eunji, Kim, Daesik, Cappellari, Ornella, Cho, Hee-Yeon, Dickson, George, Popplewell, Linda, Kim, Jin-Soo

Journal:

Molecular Therapy

Année:

2018

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2018

17

Novel Cationic Carotenoid Lipids as Delivery Vectors of Antisense Oligonucleotides for Exon Skipping in Duchenne Muscular Dystrophy

Popplewell, Linda J., Abu-Dayya, Aseel, Khanna, Tushar, Flinterman, Marcella, Khalique, Nada Abdul, Raju, Liji, Øpstad, Christer L., Sliwka, Hans-Richard, Partali, Vassilia, Dickson, George, Pungente,

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2012

18

Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides

March, James, Golshirazi, Golnoush, Cernisova, Viktorija, Carr, Heidi, Leong, Yee, Lu-Nguyen, Ngoc, Popplewell, Linda

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2018

19

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures

Hiller, Monika, Falzarano, Maria Sofia, Garcia-Jimenez, Iker, Sardone, Valentina, Verheul, Ruurd C., Popplewell, Linda, Anthony, Karen, Ruiz-Del-Yerro, Estibaliz, Osman, Hana, Goeman, Jelle J., Mamcha

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.94 MB

english, 2018

20

Editorial of the Special Issue: Antisense Therapies

Popplewell, Linda

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 154 KB

english, 2018

21

Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD)

Harish, Pradeep, Malerba, Alberto, Lu‐Nguyen, Ngoc, Forrest, Leysa, Cappellari, Ornella, Roth, Fanny, Trollet, Capucine, Popplewell, Linda, Dickson, George

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Année:

2019

Langue:

english

Fichier:

PDF, 646 KB

english, 2019

22

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Lu-Nguyen, Ngoc, Ferry, Arnaud, Schnell, Frederick J, Hanson, Gunnar J, Popplewell, Linda, Dickson, George, Malerba, Alberto

Journal:

Human Molecular Genetics

Année:

2019

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2019

23

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Lu-Nguyen, Ngoc, Ferry, Arnaud, Schnell, Frederick J, Hanson, Gunnar J, Popplewell, Linda, Dickson, George, Malerba, Alberto

Journal:

Human Molecular Genetics

Année:

2019

Fichier:

PDF, 1.95 MB

2019

24

G-quadruplex ligands mediate downregulation of DUX4 expression

Ciszewski, Lukasz, Lu-Nguyen, Ngoc, Slater, Alex, Brennan, Andrew, Williams, HuwÂ EÂ L, Dickson, George, Searle, Mark S, Popplewell, Linda

Journal:

Nucleic Acids Research

Année:

2020

Langue:

english

Fichier:

PDF, 9.42 MB

english, 2020

25

Inhibition of Myostatin Reduces Collagen Deposition in a Mouse Model of Oculopharyngeal Muscular Dystrophy (OPMD) With Established Disease

Harish, Pradeep, Forrest, Leysa, Herath, Shanti, Dickson, George, Malerba, Alberto, Popplewell, Linda

Journal:

Frontiers in Physiology

Année:

2020

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2020

26

Mutation-Directed Therapeutics for Neurofibromatosis Type I

Leier, Andre, Bedwell, David M., Chen, Ann T., Dickson, George, Keeling, Kim M., Kesterson, Robert A., Korf, Bruce R., Marquez Lago, Tatiana T., MÃ¼ller, Ulrich F., Popplewell, Linda, Zhou, Jiangbing,

Journal:

Molecular Therapy — Nucleic Acids

Année:

2020

Fichier:

PDF, 1.22 MB

2020